Advance in Helicobacter pylori resistance to clarithromycin
نویسندگان
چکیده
منابع مشابه
Helicobacter pylori primary resistance to metronidazole and clarithromycin in Brazil.
Helicobacter pylori resistance to metronidazole was detected in 107 (52.97%) of 202 strains. Twenty (9.85%) strains, 18 of them harboring 23S ribosomal DNA mutations, were resistant to clarithromycin. Metronidazole resistance was associated with female gender. Resistance to metronidazole and resistance to clarithromycin were associated. Increasing clarithromycin resistance rates were observed o...
متن کاملClarithromycin resistance and eradication of Helicobacter pylori in children.
Outcome of Helicobacter pylori infection was analyzed in 61 children treated with a triple therapy including clarithromycin. Bacterial eradication was obtained in all children with clarithromycin-susceptible strains but not in children with clarithromycin-resistant ones (P = 0.0001). H. pylori antimicrobial susceptibility is mandatory before choosing a treatment, and clarithromycin should be av...
متن کاملA Novel Reduction Strategy of Clarithromycin Resistance in Helicobacter pylori
BACKGROUND Antibiotic resistance is a major therapeutic problem in patients infected with Helicobacter pylori. H. pylori clarithromycin resistant mutants have been evolved during antibiotic therapy, this is mainly due to 23s rRNA point mutations. OBJECTIVES In the present study, we investigated anti-mutational features of four traditionally Iranian medicinal plants on three local isolated H. ...
متن کاملEvaluation of Clarithromycin and Metronidazole Resistance of Helicobacter Pylori Infection in Symptomatic Iranian Children
Helicobacter Pylori (H. pylori) as a gram-negative bacterium is the most common infection of the gastrointestinal tract, and worldwide it affects the children over three years of age. H. pylori could cause gastrointestinal and extra-intestinal manifestations. Antibiotic resistance can happen primarily and occurs during treatment. We aimed to evaluate the resistance gene of H. pylori obtained fr...
متن کاملClarithromyCin resistanCe among Helicobacter
The aims of this study were to assess primary resistance of H. pylori strains isolated from adult patients of Ilam, Iran to antibacterial agents (amoxicillin, clarithromycin, metronidazole and tetracycline) and detection of clarithromycin, azithromycin, clarithromycin, metronidazole and tetracycline resistance by disc diffusion. Fifty biopsies were taken from gastric mucosa of the antrum and bo...
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ژورنال
عنوان ژورنال: World Chinese Journal of Digestology
سال: 2008
ISSN: 2219-2859
DOI: 10.11569/wcjd.v16.i27.3060